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retatrutide and glucagon Substack Series 3 of 6: – The Next Frontier in Longevity Metabolic Health GLP-3 (R) - Triple GIP –
Fatigue is another commonly reported symptom, particularly during the early weeks
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A 2025 systematic review and meta-analysis in JAMA Psychiatry found no overall increase in psychiatric side effects, including depression, with GLP-1 medications, but individual responses still vary, which is why we monitor rather than assume
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