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Tirzepatide Cuts MACE Risk in Diabetes With Heart Disease Luke Halpern, Associate Editor Danielle Valletti, Assistant Editor , Ron Panarotti Key Takeaways A claims-based SURPASS-CVOT emulation compared tirzepatide initiators with sitagliptin as a CV-neutral proxy, using overlap-weighted propensity methods across 2 US databases from 2022 to 2025
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