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Major clinical trials show average weight loss of 5-10% by week 8, 10-15% by week 16-20, and up to 15-22% by week 52 when combined with lifestyle modifications
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GLP-1 medications quiet the “reward noise,” not the “focus circuitry.” Studies show no decline in attention or executive functioning in patients taking both medications, and many report improved emotional regulation and reduced impulsive overeating or drinking
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