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The phe1 substitution was also introduced into lixisenatide and showed similar effects (Pickford et al., 2020), as was also the case when the position 2 glycine in modified forms of exendin‐4 and lixisenatide were substituted to a “ureido” oliguria residue (Fremaux et al., 2019)
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GLP-1 agents help with cardiovascular risk, weight, hypertension, dyslipidemia—all of which affect brain blood vessels
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